About 4221 Mission Street
Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Franciscos most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses
Features of 4221 Mission Street
| MLS® # | ML82029485 |
|---|---|
| Price | $1,999 |
| Bathrooms | 0.00 |
| Lot Size | 10,084 |
| Year Built | 1977 |
| Type | Commercial Lease |
| Sub-Type | Mixed Use |
| Status | Active |
Community Information
| Address | 4221 Mission Street |
|---|---|
| City | San Francisco |
| County | San Francisco |
| Zip Code | 94112 |
Amenities
| Is Waterfront | No |
|---|---|
| Has Pool | No |
Interior
| Has Basement | No |
|---|---|
| Fireplace | No |
Exterior
| Roof | Other |
|---|
Additional Information
| Date Listed | December 15th, 2025 |
|---|---|
| Days on Market | 270 |
| Zoning | NC2 |
| Foreclosure | No |
| Short Sale | No |
| RE / Bank Owned | No |
Listing Details
| Agent | Wilson Yee |
|---|---|
| Office | Structure Properties, Inc. |